Pipsissewa acts as a urinary antiseptic and is used for bladder infections and weak bladder. It is also indicated for nephritis, swollen lymph glands, arthritis, and chronic rheumatism. This forest-loving herb is in the same family as uva-ursi (Ericaceae) and contains the same kind of antiseptic phenolic compounds. Pipsissewa is milder and safer to use when there is an acute infection or internal heat, as it is not as irritating.